Optimize your Biotech Process in all Stages
The concept of process analytical technology (PAT), initially developed in the petrochemical industry involves real-time monitoring and control of product quality during the whole manufacturing process. For biotechnological production processes, optek offers monitoring solutions in stainless and single-use, covering the upstream fermentation processes as well as the downstream purification steps including chromatography and filtration.
Fermentation
...ASD12 series probes are designed for smaller scale bioreactors used in R&D and process development areas. Extremely repeatable and easy to use, ASD12 probes come in a variety of insertion depths and o...
Monitoring High Protein Concentrations Downstream
...In filtration processes, the optimal approach to control a TFF process uses two UV sensors to monitor high protein concentrations in the retentate at an off-peak wavelength to verify the retentate con...
Centrifuge Control
...Installation of optek sensors at the inlet and at the outlet of a centrifuge greatly improves separation performance, reduces losses and improves product consistency....
Ultrafiltration
...Using an optek AF45 UV sensor on the permeate stream allows the user to ensure filter integrity, increase throughput and minimize product losses....
Chromatography
...Accurate, reliable and repeatable post-column measurements are necessary during purification to ensure accurate pooling to maximize yields and protein/DNA fraction purity....
Formulation and Filling
...Depending on the product, optek inline sensors can monitor for turbidity, color, dilution target, or even opalescence in biologics....
Single-Use Technology
...The Single Use Cell (S.U.C.) is designed to optimize separation, purification, concentration and formulation processes in disposable chromatography and ultrafiltration systems. In applications where h...
